HISTOPATHOLOGICAL FINDINGS OF ACUTE EOSINOPHILIC PNEUMONIA

TOPIC: Lung Pathology TYPE: Original Investigations PURPOSE: It has been reported that AEP histopathologically exhibits diffuse alveolar damage (DAD) with eosinophilia. However, acute respiratory distress syndrome (ARDS), interstitial pneumonia (AIP), and exacerbation of idiopathic pulmonary fibrosis, also exhibiting DAD histopathologically, are all life-threatening diseases. AFP is rapidly improved by steroids alone without remaining fibrosis or sometimes even treatment, whereas these diseases the same histopathology show greatly different clinical courses, which remains a question to solve. METHODS: Here we investigated in2surgical lung biopsy 14 TBLB cases. Additionally, determined presence absence in RESULTS: Characteristic histopathological findings consist edema infiltration eosinophils lymphocytes perivascular area interlobular septa. The spaces showed fibrinous exudates. There were no hyaline membranes massive intraluminal fibrosis. These fluid exudates radiological can explain rapid complete improvement. CONCLUSIONS: Because dose not exhibit it should be included associated CLINICAL IMPLICATIONS: We reveal true AEP. DISCLOSURES: No relevant relationships Hiroshi Mochimaru, source=Web Response